Daniel W. Armstrong, Ph.D.

Daniel W. Armstrong, Ph.D.

Daniel W. Armstrong is the R.A. Welch Distinguished Professor of Chemistry & Biochemistry at the University of Texas at Arlington. His research has spanned a wide scope, including HPLC, GC, SFC, and seminal work in enantiomeric separations and ionic liquids. His theoretical contributions spanned pseudophase, ultrafast and modeling in separations.  Most recently, Dr. Armstrong has been focused on MRR.

Dr. Armstrong has over 700 publications, including 32 book chapters, one book (“Use of Ordered Media in Chemical Separations”) and 33 patents. He has been names by the Scientific Citation Index as one of the world’s most highly cited scientists, and he has given ~ 580 invited/keynote/plenary lectures and colloquia worldwide. His work has been cited over 41,000 times and his Hirsch index is ~ 103 (G.S.).

Daniel Armstrong is considered the “Father” of micelle and cyclodextrin-based separations, he elucidated the first chiral recognition mechanism by cyclodextrins, he was the first to develop macrocyclic antibiotics as chiral selectors, and he is one of the world’s leading authorities on the theory, mechanism, and use of enantioselective molecular interactions.  Over 30 different LC and GC columns that were originally developed in his laboratories have been commercialized and/or copied worldwide.  His work and columns were in part responsible for the chromatography and electrophoresis-led revolution in chiral separations over the last two and one half decades.  Currently, the columns, chiral selectors and techniques he developed dominate the work of analytical enantiomeric separations.

He has developed the most effective way to characterize the solvent properties of room temperature ionic liquids (RTILs).  This has proven to be an essential and effective way to explain the effect of RTILs on organic reactions, and in various analytical methodologies.  Surfactant aggregation to form normal micelles in RTILs was demonstrated.  The first MALDI-MS matrices and high stability GC stationary phases based on RTILs were developed in his laboratories and were recently commercialize by Supelco/Sigma/Aldrich.  The new enhanced mass spectrometry technique of PIESI (Paired Ion Electrospray Ionization) was developed in his laboratory and is one of the most  sensitive methods for ultra-trace anion analyses and speciation.  He developed the first high efficiency CE separation approach for microorganisms (i.e., bacterial, viruses, fungi, etc.).  This will extend the realm of separation science into the mainstream of biology and colloid science.

He founded or co-founded two separate companies focused on production of novel separation media and using them for difficult analyses.