POSTER

Bridging Gaps for Analysis of Challenging Residual Solvents Using MRR

Summary

 Analyzing acetic acid and dimethyl sulfoxide (DMSO) in Emergen-C dietary supplements can be challenging.  While the United States Pharmacopeia (USP) General Chapter <467> recommends static headspace gas chromatography (SH-GC) for residual solvent testing, this technique can leave important analytical gaps.

Molecular rotational resonance (MRR) provides an alternative. This spectroscopic approach directly and unambiguously identifies molecular structure and enables fast, reliable, and fully automated quantitation without chromatographic separation. It delivers exceptional sensitivity and selectivity, helping streamline and accelerate residual solvent analysis while supporting compliance with USP and ICH guidelines.        

Download the poster to see how MRR can overcome the limitations of conventional SH-GC techniques for pharmaceutical products and dietary supplements.