Fast & Reliable Quantitation of Challenging Residual Solvents in Dietary Supplements Using MRR

Residual solvent analysis is a critical quality and safety requirement for dietary supplements, food additives, pharmaceutical excipients, and natural products. However, conventional methods often struggle with low-volatility solvents, complex sample matrices, lengthy chromatographic separations, and challenging analytes that require specialized workflows.

Molecular rotational resonance (MRR) spectroscopy offers a structure-specific alternative for residual solvent analysis. By measuring unique molecular fingerprints, MRR can distinguish structurally similar compounds without chromatographic separation, enabling fast, reliable identification and quantitation with minimal sample preparation.

In this webinar by Alex Mikhonin, Ph.D., you'll see real-world examples of residual solvent testing in:

• Dietary supplements containing acetic acid and DMSO

• Food additives and pharmaceutical excipients such as glycerol, polysorbates, and PEG

• Ashwagandha extract

• Rosemary oil containing pyridine

• Peppermint Oil spiked with multiple USP residual solvents

You'll also learn how MRR helps address analytical gaps in conventional methods, simplifies workflow development, and enables selective analysis across multiple solvent classes in a single run.