APPLICATION NOTES

Direct Quantitation of Regioisomers

MRR enables rapid identification and quantitation of challenging impurities during pharmaceutical development.

Screen Shot 2023-11-15 at 1.43.07 PM

Download now!

Fill out the form below to access a copy of your guide.

Regioisomer Quantitation

Even though regioisomers (also known as ‘positional isomers’) have the same molecular formula, their specific functional groups are located at different positions within a parent molecular structure or chain. This difference in molecular geometry may significantly impact both efficiency and safety of a drug product. Therefore, identification and quantitation of regioisomer impurities is a very important task for pharmaceutical industry at essentially all stages of drug discovery and production: from raw materials and intermediates to drug candidates and final drug products.

Yet, this task poses serious challenges for conventional analytical techniques including chromatography and mass spectrometry (MS). 

Contact Us

Get in touch to learn more about how BrightSpec can help you revolutionize the structural identification and quantitation of your small molecules.