Novel Insight into Site Specific Deuteration

MRR enables rapid method development as well as simple identification and quantitation of residual solvents in pharmaceutical products.

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A Novel Method for Measuring Site-Specific Deuteration

Deuteration has long held the promise of improving drug stability and reducing toxicity, among other
benefits. Until now, a general method to install deuterium into a small molecule in a highly selective
manner was unavailable. In the Journal of the American Chemical Society article, Prof. Clark details
novel chemistry that allows for site-specific deuteration to access deuterated small molecules with
high levels of isotopic purity.

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