Resources Library

Learn More About Everything MRR

 

Explore educational content, technical resources, and expert insights to help you learn more about molecular rotational resonance (MRR) spectroscopy and its applications. Browse our collection of application notes, posters, brochures, publications, and webinars.

Homepage Simulation v2

 

Application Notes

App Note

Beyond Mass: Structure-Specific Quantitation of Closely Related Impurities in Pharmaceutical Raw Materials

   August 2025

App Note

Accelerating Forced Degradation Studies with Molecular Rotational Resonance Spectroscopy: Targeted Analysis of Caffeic Acid Degradation Products

July 2026

App Note

Rethinking Routine Quality Control for Food & Beverage: Direct Analysis of Representative Volatile Quality Markers in Fortified Wine

July 2026

App Note

Structure-Specific Identification of Impurities in Complex Mixtures Using MRR

June 2026

App Note

Unambiguous Identification of Candidate CompoundsUsing MRR Structure Validation

May 2026

App Note

Structure Validation: Automated MRR Library Building for Confident Molecular Identification

April 2026

App Note

Direct Quantitative Analysis of Formaldehyde in Aqueous Samples Using MRR with SpectrAline Cartridges and the spectraMRR

March 2026

App Note - Structure ID

Same Formula, Different Story: Unambiguous Identification of Stereoisomers Using Molecular Rotational Resonance Spectroscopy

February 2026

App Note

Where Precision Meets Throughput: Molecular Rotational Resonance Spectroscopy for Ethylene Glycol and Diethylene Glycol Excipient Safety Testing

   December 2025

App Note

Tracking Ethylene Oxide and Acetaldehyde in PEG-3350: How Molecular Rotational Resonance Spectroscopy Outpaces Gas Chromatography

   October 2025

App Note

Breaking the Standard: Alaninol Chirality Confirmed Without Chromatography

June 2025

App Note

Ditching Derivatization: Molecular Rotational Resonance Spectroscopy for Formaldehyde Quantitation

May 2025

App Note

No Standards, No Problem: Molecular Rotational Resonance Spectroscopy Cracks the Chiral Code

  April 2025

App Note

Unmasking Essential Oil Authenticity with Molecular Rotational Resonance Spectroscopy

   February 2025

App Note

Molecular Rotational Resonance Spectroscopy: An Agile Solution for Residual Analysis in Pharmaceutical Products

   March 2025

App Note

Direct Analysis of Class 2 Residual Solvents Using Molecular Rotational Resonance Spectroscopy ©2024 USPC

   2024

 

 

 

 

 

Posters

Poster

Enabling High-Throughput Natural Product Identification through Molecular Rotational Resonance (MRR) Spectral Libraries

July 2026

Poster

Standards-Free Structural Elucidation of Natural Products Using Molecular Rotational Resonance (MRR) Spectroscopy

July 2026

Poster

Unambiguous Structural Identification Without Reference Standards Using MRR

June 2026

Poster

Direct Headspace-MRR Quantitation of Ethylene Glycol & Diethylene Glycol Contaminants in Glycerin

   June 2026

Poster

Routine Characterization of Enantiomerically Selective Reactions by Molecular Rotational Resonance (MRR) Spectroscopy

   March 2026

Poster

Development of a Spectral Library for Nitrosamine ID and Quantification in Pharmaceuticals and Consumer Products

   March 2026

Poster

High-Throughput, Fully Automated Analysis of USP <467> Residual Solvents Using Headspace MRR

   March 2026

 

Videos

Video

Molecular Rotational Resonance Spectroscopy Overview

See BrightSpec's molecular rotational resonance (MRR) spectroscopy technology in action and learn how it enables direct molecular identification and quantitation from a single measurement.

Video

Meet the spectraMRR

Explore BrightSpec’s spectraMRR™, an advanced molecular rotational resonance (MRR) spectroscopy platform that simplifies structure analysis and delivers highly selective molecular identification and quantitation. 

Video

Meet the isoMRR

Discover BrightSpec's isoMRR™, a powerful platform for precise quantification of volatile compounds, delivering confident analysis of isomers and enantiomers in a single streamlined workflow.

Video

Unique Detection for Diastereomers

Learn how molecular rotational resonance (MRR) spectroscopy distinguishes closely related diastereomers that are often difficult to differentiate using traditional methods such as gas chromatography.

 

Brochures

Brochure

Meet the Full BrightSpec-MRR Product Portfolio

Meet the spectraMRR, isoMRR and nanoMRR instruments.

Brochure

Meet the spectraMRR

Structure and quantitation simplified.

Brochure

Meet the isoMRR

Streamline your most complex analytical workflows.

Brochure

SpectraAline Cartridges

Optimized sample introduction for high-sensitivity MRR.

 

Publications

Publication

A Semi-Automated Workflow for Molecular Rotational Spectroscopy Characterization of New Molecules

June 2026 Journal of Molecular Spectroscopy

Publication

How MRR Spectroscopy Overcomes MS, GC Challenges

October 2024 labcompare

Publication

Analysis of Isomeric Mixtures Using Molecular Rotational Resonance Spectroscopy

June 2023 Analytical Science Advances

Publication

Precision Deuteration Using Cu-Catalyzed Transfer Hydro Deuteration to Access Small Molecules

June 2023 Journal of the American Chemical Society

Publication

Rapid Enantiomeric Excess Measurements of Enantioisotopomers by MRR

March 2023 Organic Process Research & Development

Publication

Essential Oil Composition and Enantioselective Profile of Agastache Urticifolia (Lamiaceae) and Monardella Odoratissima (Lamiaceae) from Utah

February 2023 Molecules

Publication

Enantioselective Synthesis of Enantioisotopomers With Quantitative Chiral Analysis by Chiral Tag MRR

June 2022 Angewandte Chemie

Publication

Chiral Analysis of Linalool, an Important Natural Fragrance and Flavor Compound, by MRR

April 2022 Symmetry

Publication

Chiral Analysis of Pantolactone with Molecular Rotational Resonance Spectroscopy

September 2021 Chirality

Publication

Enhancing Sensitivity for High-Selectivity Gas Chromatography-MRR

November 2021 Analytical Chemistry

Publication

2021 Copper-Catalyzed Transfer Hydrodeuteration of Aryl Alkenes with Quantitative Isotopomer Purity Analysis by Molecular Rotational Resonance Spectroscopy

May 2021 Journal of the American Chemical Society

Publication

Rapid Quantification of Isomeric and Dehalogenated Impurities in Pharmaceutical Raw Materials by MRR Spectroscopy

September 2020 Journal of Pharmaceutical and Biomedical Analysis

 

Webinars

Webinar

MRR for Faster, Simpler Detection of Volatile Food Contaminants in Complex Matrices

July 2026

Watch how MRR spectroscopy gives food and beverage quality and safety teams a faster, simpler, and smarter way to identify volatile compounds, even in complex matrices.

Webinar

Direct Highly-Selective Analysis of Ethylene Oxide & Acetaldehyde from Aqueous & Injection-Unfriendly Matrices for Food Safety Screening Using MRR

June 2026

Explore how MRR enables confident detection and differentiation of ethylene oxide and acetaldehyde in challenging matrices.

Webinar

Using the nanoMRR in Teaching and Research: A Chemistry Professor's Guide

February 2025

Discover how BrightSpec's nanoMRR instrument, powered by molecular rotational resonance, is being used in academic research and teaching.

Webinar

Unveiling Sesquiterpenes: Characterizing Isomers with MRR Spectroscopy

May 2022

See how MRR can characterize the stereoisomers of sesquiterpenes without the need for reference samples.

Webinar

Everyday Authenticity: A Novel Approach to Tea Tree Oil Characterization

February 2022

Learn how MRR can be used to validate product authenticity and improve product quality.

Webinar

Application of MRR Spectroscopy in Drug Development

June 2021

GSK presents how structural analysis with MRR simplifies chemical analysis during pharmaceutical development.

Webinar

MRR - A Powerful Analytical Technique for Industrial Chemistry

March 2021

BASF presents how MRR fits into their analytical toolkit and provides a powerful orthogonal approach.

Webinar

Introduction to MRR Principles and Instrumentation

March 2012

Our CTO, Justin Neil, PhD, gives an introduction to the foundational principle of rotational spectroscopy.

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