Expand Residual Solvent Analysis Beyond the Limits of Conventional Gas Chromatography

This application note demonstrates how molecular rotational resonance (MRR) spectroscopy enables direct analysis of residual solvents across a broad range of pharmaceutical manufacturing workflows. Using USP Class 2 residual solvents as examples, MRR delivers highly selective identification and quantitation without chromatographic separation while supporting analysis of challenging low-volatility solvents that are difficult to measure using conventional headspace gas chromatography methods.

Application Note Highlights

• Learn how MRR directly identifies and quantifies residual solvents without chromatographic separation.

• Explore the analysis of challenging low-volatility solvents, including compounds from USP Class 2 Mixture C.

• See validation data demonstrating selectivity, linearity, repeatability, and recovery across pharmaceutical matrices.

• Understand how MRR supports pharmaceutical development, manufacturing, and quality control through streamlined residual solvent analysis.

Download the application note to learn more.