Simplify PEG Excipient Testing with Direct Impurity Analysis

This application note demonstrates how molecular rotational resonance (MRR) spectroscopy enables direct detection and quantitation of ethylene oxide (EtO) and acetaldehyde in PEG-3350 excipents. Using automated headspace sampling, MRR eliminates complex sample preparation and method development while delivering the sensitivity, speed, and reliability required for excipient quality and compliance testing.

Application Note Highlights

• Learn how MRR directly measures ethylene oxide and acetaldehyde in PEG-3350 using headspace analysis.

• Compare streamlined MRR workflows with traditional GC-MS methods for impurity testing.

• Explore quantitative performance demonstrating strong linearity and sensitivity aligned with USP acceptance criteria.

• See how automated analysis supports high-throughput excipient quality and compliance workflows.

Download the application note to learn more.