Simplify Excipient Safety Testing with Direct EG and DEG Quantitations

This application note demonstrates how molecular rotational resonance (MRR) spectroscopy enables direct quantitation of ethylene glycol (EG) and diethylene glycol (DEG) in PEG-400 for excipient safety testing. Using automated headspace sampling, MRR eliminates dilution, filtration, and derivatization while delivering sensitive, low-ppm quantitation with the speed, reliability, and confidence required for pharmaceutical quality control workflows.

Application Note Highlights

• Learn how MRR directly quantifies EG and DEG in PEG-400 without dilution, filtration, or derivatization.

• Compare streamlined headspace-MRR workflows with traditional GC-MS methods for excipient safety testing.

• Explore quantitative performance data demonstrating low-ppm detection limits, strong linearity, and excellent repeatability.

• See how automated sampling and BrightSpec's Edgar^TM software support high-throughput pharmaceutical quality control workflows.

Download the application note to learn more.