spectraMRR instrument MRR

Application Note

Same Formula, Different Story: Unambiguous Identification of Stereoisomers Using Molecular Rotational Resonance Spectroscopy

 

 

Resolve Stereochemical Ambiguity in Natural Product Analysis

This application note demonstrates how molecular rotational resonance (MRR) spectroscopy enables unambiguous identification of closely related stereoisomers in complex mixtures. Using sesquiterpene alcohols commonly encountered in natural product and essential oil analysis, MRR combines simulated and experimental rotational spectra to confirm molecular identity without chromatographic separation or reference standards.

Application Note Highlights

  • Learn how MRR differentiates closely related stereoisomers that share the same molecular formula and core structure.

  • Explore how BrightSpec's BrightHubTM software generates simulated rotational spectra for candidate structures before analysis.

  • See how unique rotational fingerprints enable definitive identification of viridiflorol, globulol, and related sesquiterpenes.

  • Understand how structure-specific identification supports authenticity testing, chemotype verification, and quality control workflows.

Download the application note to learn more.

 

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