Resources Library
Learn More About Everything MRR
Explore educational content, technical resources, and expert insights to help you learn more about molecular rotational resonance (MRR) spectroscopy and its applications. Browse our collection of application notes, posters, brochures, publications, and webinars.

Application Notes
App Note
Beyond Mass: Structure-Specific Quantitation of Closely Related Impurities in Pharmaceutical Raw Materials
August 2025
App Note
Accelerating Forced Degradation Studies with Molecular Rotational Resonance Spectroscopy: Targeted Analysis of Caffeic Acid Degradation Products
July 2026
App Note
Rethinking Routine Quality Control for Food & Beverage: Direct Analysis of Representative Volatile Quality Markers in Fortified Wine
July 2026
App Note
Structure-Specific Identification of Impurities in Complex Mixtures Using MRR
June 2026
App Note
Unambiguous Identification of Candidate CompoundsUsing MRR Structure Validation
May 2026
App Note
Structure Validation: Automated MRR Library Building for Confident Molecular Identification
April 2026
App Note
Direct Quantitative Analysis of Formaldehyde in Aqueous Samples Using MRR with SpectrAline Cartridges and the spectraMRR
March 2026
App Note - Structure ID
Same Formula, Different Story: Unambiguous Identification of Stereoisomers Using Molecular Rotational Resonance Spectroscopy
February 2026
App Note
Where Precision Meets Throughput: Molecular Rotational Resonance Spectroscopy for Ethylene Glycol and Diethylene Glycol Excipient Safety Testing
December 2025
App Note
Tracking Ethylene Oxide and Acetaldehyde in PEG-3350: How Molecular Rotational Resonance Spectroscopy Outpaces Gas Chromatography
October 2025
App Note
Breaking the Standard: Alaninol Chirality Confirmed Without Chromatography
June 2025
App Note
Ditching Derivatization: Molecular Rotational Resonance Spectroscopy for Formaldehyde Quantitation
May 2025
App Note
No Standards, No Problem: Molecular Rotational Resonance Spectroscopy Cracks the Chiral Code
April 2025
App Note
Unmasking Essential Oil Authenticity with Molecular Rotational Resonance Spectroscopy
February 2025
App Note
Molecular Rotational Resonance Spectroscopy: An Agile Solution for Residual Analysis in Pharmaceutical Products
March 2025
App Note
Direct Analysis of Class 2 Residual Solvents Using Molecular Rotational Resonance Spectroscopy ©2024 USPC
2024
Posters
Poster
Enabling High-Throughput Natural Product Identification through Molecular Rotational Resonance (MRR) Spectral Libraries
July 2026
Poster
Standards-Free Structural Elucidation of Natural Products Using Molecular Rotational Resonance (MRR) Spectroscopy
July 2026
Poster
Unambiguous Structural Identification Without Reference Standards Using MRR
June 2026
Poster
Direct Headspace-MRR Quantitation of Ethylene Glycol & Diethylene Glycol Contaminants in Glycerin
June 2026
Poster
Routine Characterization of Enantiomerically Selective Reactions by Molecular Rotational Resonance (MRR) Spectroscopy
March 2026
Poster
Development of a Spectral Library for Nitrosamine ID and Quantification in Pharmaceuticals and Consumer Products
March 2026
Poster
High-Throughput, Fully Automated Analysis of USP <467> Residual Solvents Using Headspace MRR
March 2026
Videos
Video
Molecular Rotational Resonance Spectroscopy Overview
See BrightSpec's molecular rotational resonance (MRR) spectroscopy technology in action and learn how it enables direct molecular identification and quantitation from a single measurement.
Video
Meet the spectraMRR
Explore BrightSpec’s spectraMRR™, an advanced molecular rotational resonance (MRR) spectroscopy platform that simplifies structure analysis and delivers highly selective molecular identification and quantitation.
Video
Meet the isoMRR
Discover BrightSpec's isoMRR™, a powerful platform for precise quantification of volatile compounds, delivering confident analysis of isomers and enantiomers in a single streamlined workflow.
Video
Unique Detection for Diastereomers
Learn how molecular rotational resonance (MRR) spectroscopy distinguishes closely related diastereomers that are often difficult to differentiate using traditional methods such as gas chromatography.
Brochures
Brochure
Meet the Full BrightSpec-MRR Product Portfolio
Meet the spectraMRR, the isoMRR and the nanoMRR.
A Semi-Automated Workflow for Molecular Rotational Spectroscopy Characterization of New Molecules
June 2026 Journal of Molecular Spectroscopy
Analysis of isomeric mixtures using molecular rotational resonance spectrsoscopy
2023 Analytical Science Advances
Precision deuteration using Cu-catalyzed transfer hydrodeuteration to access small molecules
2023 Journal of the American Chemical Society
Rapid Enantiomeric Excess Measurements of Enantioisotopomers by MRR
2023 Organic Process Research and Development
Journal of the American Chemical Society
2020 Journal of Pharmaceutical and Biomedical Analysis
MRR for Faster, Simpler Detection of Volatile Food Contaminants in Complex Matrices
July 2026
Watch how MRR spectroscopy gives food and beverage quality and safety teams a faster, simpler, and smarter way to identify volatile compounds, even in complex matrices.
June 2026
Explore how MRR enables confident detection and differentiation of ethylene oxide and acetaldehyde in challenging matrices.
Using the nanoMRR in Teaching and Research: A Chemistry Professor's Guide
February 2025
Discover how BrightSpec's nanoMRR instrument, powered by molecular rotational resonance, is being used in academic research and teaching.
Unveiling Sesquiterpenes: Characterizing Isomers with MRR Spectroscopy
May 2022
See how MRR can characterize the stereoisomers of sesquiterpenes without the need for reference samples.
Everyday Authenticity: A Novel Approach to Tea Tree Oil Characterization
February 2022
Learn how MRR can be used to validate product authenticity and improve product quality.
Application of MRR Spectroscopy in Drug Development
June 2021
GSK presents how structural analysis with MRR simplifies chemical analysis during pharmaceutical development.
MRR - A Powerful Analytical Technique for Industrial Chemistry
March 2021
BASF presents how MRR fits into their analytical toolkit and provides a powerful orthogonal approach.
Introduction to MRR Principles and Instrumentation
March 2012
Our CTO, Justin Neil, PhD, gives an introduction to the foundational principle of rotational spectroscopy.
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